A journey through the studies behind STOP2030

The development
of fixed-dose ivermectin
STOP Projects
Co-administration of
albendazole and ivermectin
Registry
Fixed-dose ivermectin use for MDA campaigns
Exploring the feasibility of fix dose regimens of ivermectin for Mass Drug Administration activities for the control of STH and other NTDs. PROSPERO 2024

2024

Registry
REALISE Clinical Trial
FDC Expanded Safety and Effectiveness

2023

Grant
STOP2030
Towards the interruption of transmission of soil-transmitted helminths: promoting implementation of research results of a fixed-dose combination of coformulated ivermectin and albendazole.
Publication
Fixed-dose ivermectin in the COVID-19 pandemic
Safety and Efficacy of a MEURI Program for the Use of High Dose Ivermectin in COVID-19 Patients.

2022

Publication
ALIVE Clinical Trial
An adaptive phase II/III safety and efficacy randomized controlled trial of single day or three-day fixed-dose albendazole-ivermectin co-formulation versus albendazole for the treatment of Trichuris trichiura and other STH infections.
Publication
FDC Characterization
Pharmacokinetic Characterization and Comparative Bioavailability of an Innovative Orodispersible Fixed-Dose Combination of Ivermectin and Albendazole: A Single Dose, Open Label, Sequence Randomized, Crossover Clinical Trial in Healthy Volunteers.
Publication
Ivermectin and albendazole for S. stercolaris
Ivermectin and albendazole coadministration: opportunities for strongyloidiasis control..

2021

Publication
Ivermectin and albendazole for T. trichiura
Efficacy and Safety of Albendazole and High-Dose Ivermectin Coadministration in School-Aged Children Infected With Trichuris trichiura in Honduras: A Randomized Controlled Trial.
Publication
Fixed-dose ivermectin safety studies
Safety of high-dose ivermectin: a systematic review and meta-analysis.

2020

Publication
First trials of the fixed-dose ivermectin
Safety and pharmacokinetic profile of fixed-dose ivermectin with an innovative 18mg tablet in healthy adult volunteers.

2018

2017

Grant
STOP I and II
Towards the interruption of transmission of soil-transmitted helminths: Clinical research development of a fixed-dose co-formulation of ivermectin and albendazole.
Publication
Ivermectin and albendazole for S. stercolaris and hookworm
Albendazole and ivermectin for the control of soil-transmitted helminths in an area with high prevalence of Strongyloides stercoralis and hookworm in northwestern Argentina: A community-based pragmatic study.

2017

Publication
Identification of the burden of S. stercolaris 
A Public Health Response against Strongyloides stercoralis: Time to Look at Soil-Transmitted Helminthiasis in Full